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You may report side effects to Health Canada at Before taking this medication, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of:. This drug may make you dizzy or drowsy.

Alcohol or marijuana cannabis can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana cannabis. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Levodopa passes into breast milk in small amounts and may affect how much milk you make. It is unknown if carbidopa passes into breast milk. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Taking MAO inhibitors with this medication may cause a serious possibly fatal drug interaction. Avoid taking MAO inhibitors isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication.

However, certain MAO inhibitors rasagiline, safinamide, selegiline may be used with careful monitoring by your doctor. Ask your doctor when to start or stop taking this medication. Make sure laboratory personnel and all your doctors know you use this drug.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call Otherwise, call a poison control center right away. US residents can call their local poison control center at Canada residents can call a provincial poison control center. Consult your doctor for more details. People with Parkinson's disease may have an increased risk for developing skin cancer melanoma. Tell your doctor promptly if you have a mole that gets bigger or looks different, or if you have other unusual skin changes.

Ask your doctor if you should have regular skin exams. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. Store at room temperature away from light and moisture. Do not store in the bathroom.

Keep all medications away from children and pets. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label.

The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. There is a problem with information submitted for this request.

Sign up for free, and stay up-to-date on research advancements, health tips and current health topics, like COVID, plus expert advice on managing your health. Error Email field is required. Error Include a valid email address. The dispersion is a bright orange colour and will stain enteral tubes, skin and clothing.

Entacapone does not fully dissolve in water, so if giving via enteral feeding tube, the tube should be well flushed after administration. Avoid crushing tablets as this produces red dust which will stain. Crushed tablets may be administered orally with jam, honey or orange juice to cover bitter taste. Amantadine is highly soluble in water. For long-term use consider transferring to syrup.

If the syrup is used, monitor total daily intake of sorbitol. Parkinson's disease - alternative ways to administer medication exp date isn't null, but text field is. Go to algorithm. Important notes - please read before using the information in these pages. This is general information and may not apply to all patients. Crushing or dispersing non-dispersible tablets means that the medicine will be administered outwith the terms of its product license with liability being assumed by all those involved in the medicines administration process, including prescriber, dispensing pharmacist and nurses administering the medicine.

Use tablet crushers designed specifically for this purpose, these can be obtained through PECOS system. Where tablets are dispersed ensure that the whole tablet content is rinsed from tablet crushers, medicine pots and oral syringes and administered to the patient.

Poorly soluble crushed tablets may pose an aspiration risk for patients with swallowing difficulties. Aim for a liquid with a uniform consistency. Crush or disperse tablets immediately prior to administration. It is not necessarily covert if given by NG, PEG or patch but it may be considered to be if the individual is not told that medication is being given.

To avoid this please advise the individual that they are receiving their medication in this way. If they do not have capacity or are unconscious this may need to be discussed with their welfare attorney or guardian.



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